Legendary Hollywood film-maker and actor Rob Reiner and his wife Michele have been found dead in their Los Angeles home.

Authorities are investigating the incident as an apparent homicide after police and firefighters were called to the couple's house on Sunday afternoon in an upmarket neighbourhood of LA.

Reiner is known for directing classic films including The Princess Bride, This is Spinal Tap, When Harry Met Sally, Misery and A Few Good Men.

"It is with profound sorrow that we announce the tragic passing of Michele and Rob Reiner," a family spokesperson said in a statement to US media.

"We are heartbroken by this sudden loss, and we ask for privacy during this unbelievably difficult time."

Police said a 78-year-old man and 68-year-old woman were pronounced dead at the home, but officers did not immediately identify the couple or the circumstances surrounding their deaths.

Police also said no-one had been arrested, but that no suspect or person of interest was currently being sought.

A spokesperson for the Los Angeles Fire Department told the BBC they received a call at about 15:38 local time (23:38 GMT) for medical aid to a home in Brentwood, a neighbourhood that is home to many celebrities.

Robbery homicide detectives from the LA police department also responded to the home and have opened a homicide investigation.

In a news conference on Sunday night, police did not offer any details about the deaths or what they found when they responded. Deputy Chief Alan Hamilton said both bodies were still inside the house, more than six hours after police and firefighters had been called.

Police also did not give details about any injuries the pair sustained, nor if any weapon was found or used. Hamilton said a cause of death would be determined by the LA coroner's office.

'Big-hearted genius'

California Governor Gavin Newsom released a statement that confirmed the death of Reiner and his wife.

Newsom said he was "heartbroken" by the deaths and called Reiner a "big-hearted genius behind so many of the classic stories we love".

Rob Reiner, the son of comedy great Carl Reiner, started his career in the 1960s and made it big playing Meathead in groundbreaking TV sitcom All in The Family in the 1970s.

The show was a US remake of British comedy Till Death Us Do Part, and scored him two Emmy Awards.

Reiner achieved futher success with cult mockumentary This Is Spinal Tap in 1984, which he directed as well as playing on-screen director Marty DiBergi.

That began a run of classic Hollywood movies directed by Reiner, including Stand By Me (1986), The Princess Bride (1987), When Harry Met Sally (1989), Misery (1990) and A Few Good Men (1992), the latter of which scored him an Academy Award nomination for best picture.

He reunited with Spinal Tap for long-awaited sequel Spinal Tap II: The End Continues, which was released this September.

As an actor, he also appeared in The Wolf of Wall Street, Postcards from the Edge and Bullets Over Broadway, as well as TV shows including New Girl and The Bear.

Those paying tribute included former US President Barack Obama, who said he and wife Michelle were heartbroken by the couple's deaths.

"Rob's achievements in film and television gave us some of our most cherished stories on screen," he said. "But beneath all of the stories he produced was a deep belief in the goodness of people - and a lifelong commitment to putting that belief into action.

"Together, he and his wife lived lives defined by purpose. They will be remembered for the values they championed and the countless people they inspired. We send our deepest condolences to all who loved them."

Further tributes came from the TV and film world, with Monty Python star Eric Idle describing Reiner as "a lovely man".

'A huge loss'

"I spoke to him last night for over an hour," Idle wrote on X. "I always enjoyed his company.

"I met him at his Dad's in 1975. He was telling me about fiming at Stonehenge and his thoughts for the future. This is so awful. I shall miss him. A clever, talented and very thoughtful man. So awful."

Actor John Cusack called Reiner "a great man", while Elijah Wood said he was "horrified" by the couple's deaths.

James Woods, who was nominated for an Oscar for starring in Reiner's 1996 drama Ghosts of Mississippi, said he was "devastated by this terrible event".

Comedy star and director Ben Stiller said it was "a huge loss".

"Rob Reiner was one of my favorite directors," he wrote. "He made some of the most formative movies for my generation.

"He came out from behind a huge comedic shadow of the great Carl Reiner and being a TV actor to being a a great director who made an incredible run of movies.

"Spinal Tap is one of the best comedies ever made - and the list goes on. He was a kind caring person who was really really funny."

Frozen actor Josh Gad described Reiner as "one of the greatest directors of our time".

"He was simply a beautiful person," he said. "Rob Reiner and his wife Michelle were two of the most kind and caring souls you could ever imagine.

"He cared so much for those who had no voices. This loss is devastating. I cannot express how much this hurts. Love you Rob and Michelle. Thank you for all you gave us."

'Powerful voice'

Reiner also co-founded the successful Castle Rock Entertainment production company.

He was married to Laverne & Shirley actress Penny Marshall from 1971 to 1981 and is the adoptive father to Marshall's daughter, actress Tracy Reiner.

He married Michele Reiner, an actress, photographer and producer, in 1989. The couple have three children together.

Michele owned the Reiner Light photography agency and production house.

LA mayor Karen Bass called the incident a "devastating loss for our city and country", and paid tribute to the couple's charity work for childhood development and LGBTQ+ advocacy.

"Rob Reiner's contributions reverberate throughout American culture and society, and he has improved countless lives through his creative work and advocacy fighting for social and economic justice," she said.

Reiner was also an active campaigner for social and political causes, and for Democratic political candidates.

Gov Newsom added: "Rob was a passionate advocate for children and for civil rights - from taking on Big Tobacco, fighting for marriage equality, to serving as a powerful voice in early education."