Ghana defender Harrison Afful is set for a two-week spell on the sidelines after picking up a hamstring injury last Tuesday.
The Esperance right-back has already suffered a sprained right knee and a lesion of the right thigh muscle and a sprained left ankle thi season.
The former Asante Kotoko player is expected to recover fully before the seasons end.
Esperance are on top of the Tunisian League table with a two-point advantage after 20 rounds of matches.