Kotoko will be without captain Amos Frimpong for Sunday's clash against Ebusua Dwarfs.
The experienced right-back is on international duty with Ghana's Local Black Stars, who are billed to play a friendly against Japan's U23 side.
Frimpong, 25, has been named in Maxwell Konadu's 17-man squad for the international friendly at the Best amenity Stadium in Saga.
His absence will give youngster Attah Kusi an opportunity to stake a claim in the team.