District Results of Presidential Elections 2000 for Assin South
| Candidate | Votes | Percentage (%) |
| Mills | 10116 | 38 |
| Kuffuor | 15597 | 58.6 |
| Goosie | 282 | 1.1 |
| Hagan | 205 | 0.8 |
| Mahama | 75 | 0.3 |
| Wereko Brobby | 63 | 0.2 |
| Lartey | 269 | 1 |
| Valid | 0 | 0 |
| Rejected | 0 | 0 |
| Total Turnout | 0 | 0 |
| Registered | 0 |